Ilio Vitale Selected Research

Tetraploidy

1/2017	Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.
1/2016	Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
2/2014	Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention.
2/2013	Immunosurveillance against tetraploidization-induced colon tumorigenesis.
1/2013	An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells.
1/2013	Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations.
7/2010	Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells.
5/2009	p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.
4/2009	Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.
7/2008	Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.

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Ilio Vitale Research Topics

Disease

57	Neoplasms (Cancer) 04/2021 - 12/2007
14	Tetraploidy 01/2017 - 06/2006
7	Carcinogenesis 01/2017 - 01/2011
6	Carcinoma (Carcinomatosis) 02/2014 - 05/2007
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2013 - 01/2007
4	Colorectal Neoplasms (Colorectal Cancer) 04/2021 - 01/2013
4	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018 - 03/2010
4	Polyploidy 02/2014 - 05/2007
3	Genomic Instability 01/2018 - 07/2010
3	Lung Neoplasms (Lung Cancer) 11/2014 - 05/2008
2	Disease Progression 01/2019 - 02/2013
2	Breast Neoplasms (Breast Cancer) 03/2017 - 11/2014
2	Triple Negative Breast Neoplasms 02/2017 - 12/2015
2	Aneuploidy (Aneuploid) 01/2017 - 01/2013
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 06/2016 - 01/2016
2	Necrosis 01/2016 - 01/2011
2	Hypoxia (Hypoxemia) 02/2013 - 06/2008
1	Melanoma (Melanoma, Malignant) 12/2021
1	Stomach Neoplasms (Stomach Cancer) 01/2017
1	Infections 01/2017
1	Residual Neoplasm 12/2015
1	Neoplasm Metastasis (Metastasis) 11/2015
1	Multiple Myeloma 04/2015
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 04/2015
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 11/2014
1	Colonic Neoplasms (Colon Cancer) 02/2014

Drug/Important Bio-Agent (IBA)

11	Cisplatin (Platino)FDA LinkGeneric 11/2014 - 06/2006
9	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 06/2006
7	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 01/2011
7	Proteins (Proteins, Gene)FDA Link 03/2017 - 04/2009
5	Phosphotransferases (Kinase)IBA 03/2017 - 07/2008
4	CalreticulinIBA 01/2020 - 12/2009
4	Poly(ADP-ribose) Polymerase InhibitorsIBA 03/2016 - 03/2013
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2018 - 06/2012
3	Biomarkers (Surrogate Marker)IBA 02/2017 - 12/2015
3	Oncogene Proteins (Oncogene Protein)IBA 06/2016 - 06/2011
3	AnthracyclinesIBA 11/2015 - 11/2014
2	prexasertibIBA 04/2021 - 01/2018
2	Caspase 2IBA 12/2020 - 01/2017
2	AntigensIBA 01/2020 - 10/2013
2	Interferon Type IIBA 01/2017 - 11/2014
2	Cytochromes c (Cytochrome c)IBA 01/2016 - 03/2013
2	CaspasesIBA 01/2016 - 03/2013
2	VaccinesIBA 10/2014 - 09/2013
2	Vitamin B 6IBA 02/2013 - 08/2012
2	pyrazolanthroneIBA 01/2013 - 06/2012
2	Cytotoxins (Cytolysins)IBA 08/2012 - 12/2006
2	Sirolimus (Rapamycin)FDA Link 01/2012 - 06/2008
2	MicroRNAs (MicroRNA)IBA 01/2011 - 03/2010
2	Histones (Histone)IBA 03/2010 - 04/2009
2	Epothilones (Epothilone)IBA 01/2010 - 07/2008
2	TubulinIBA 07/2008 - 05/2008
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2006 - 06/2006
2	CamptothecinIBA 12/2006 - 06/2006
1	Retroelements (Retrotransposon)IBA 12/2021
1	Histone-Lysine N-MethyltransferaseIBA 12/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Programmed Cell Death 1 ReceptorIBA 01/2020
1	Granzymes (Granzyme)IBA 01/2020
1	SuspensionsIBA 01/2020
1	OvalbuminIBA 01/2020
1	Interferon-gamma (Interferon, gamma)IBA 01/2020
1	PlasticsIBA 01/2019
1	EpitopesIBA 01/2019
1	human ERBB2 proteinIBA 03/2017
1	A-Form DNA (A-DNA)IBA 02/2017
1	Antiviral Agents (Antivirals)IBA 01/2017
1	EnzymesIBA 03/2016
1	Protein Kinases (Protein Kinase)IBA 01/2016
1	LTX-315IBA 01/2016
1	Retinoblastoma ProteinIBA 01/2016
1	Hormones (Hormone)IBA 12/2015
1	Therapeutic UsesIBA 11/2015
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 11/2015
1	LigandsIBA 11/2015
1	Checkpoint Kinase 2IBA 10/2015
1	InterferonsIBA 08/2015
1	Proteasome InhibitorsIBA 04/2015
1	carfilzomibIBA 04/2015
1	Bortezomib (Velcade)FDA Link 04/2015
1	NAD (NADH)IBA 11/2014
1	Adenine FDA LinkGeneric 11/2014
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2014
1	Nicotine FDA Link 11/2014
1	obatoclaxIBA 11/2014
1	Antimitotic AgentsIBA 02/2014
1	ProdrugsIBA 02/2014
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2014
1	SalicylatesIBA 02/2014
1	ResveratrolIBA 02/2014

Therapy/Procedure

17	Therapeutics 04/2021 - 01/2011
12	Drug Therapy (Chemotherapy) 01/2018 - 12/2006
6	Radiotherapy 05/2017 - 12/2006
3	Immunotherapy 01/2021 - 01/2019
3	Neoadjuvant Therapy 06/2016 - 12/2015
1	Nutritional Support (Artificial Feeding) 01/2019
1	Adjuvant Chemotherapy 11/2015
1	Lab-On-A-Chip Devices 11/2015
1	Radioimmunotherapy 10/2014
1	Chemoprevention 02/2014